马晓强 职      称：长聘教轨副教授（博士生导师，独立PI） 所属学科：食品科学与工程，食品生物技术 研究方向：食品合成生物学 电子信箱：xq_ma@sjtu.edu.cn 联系地址：农生创新楼B-227 实验室地址：农生创新楼B-214A

 

个人介绍：

      马晓强博士长期从事食品微生物和酶工程、食品合成生物学技术开发和应用研究，目前主持国家及企业项目3项；在 Nat. Commun、PNAS、Sci. Adv、Curr. Opin. Biotechnol、J. Agric. Food. Chem等期刊发表SCI论文30余篇，第一作者发表文章14篇，多次受邀国际会议报告，获上海海外高层次引进人才荣誉。

 

研究领域：

   1．食品生物质高值化、功能化利用

   2．食品酶/微生物及群落工程合成高值食品农业化合物

   3.  食品合成生物学技术开发和应用

 

教育与工作经历：

2021 – 至今  金沙2004路线js5， 金沙2004路线js5，食品科学与工程系，PI

2018 – 2021 新加坡-麻省理工学院学术联盟， 精准农业创新性技术开发部，博士后

2015 – 2018 新加坡国立大学，工程学院， 化学与生物分子系，博士后

2010 – 2015 华东理工大学， 生物化工， 博士

2006 – 2010 山西农业大学 ，生物科学， 学士

 

代表性论文：

1. Ma, X., Liang, H., Pan, Q., Prather, K. L., Sinskey, A. J., Stephanopoulos, G., & Zhou, K. (2022). Optimization of the isopentenol utilization pathway for isoprenoid synthesis in Escherichia coli. Journal of Agricultural and Food Chemistry, 70(11), 3512-3520.

2. Ma, X., H. Liang., S. Panda., V. Fung., J. Zhou and K. Zhou* (2022). C2 feedstock-based biomanufacturing of value-added chemicals. Current Opinion in Biotechnology 73:240-245.

3. Wu, S, X. Ma (Co-first author)., A. Zhou., A. Valenzuela., K. Zhou*. and Y. Li* (2021). Establishment of strigolactone-producing bacterium-yeast consortium. Science Advances 7(38):1-13.

4. Ma, X., Gözaydın. G., Yang. H., W. Ning., Han. Xi., Poon. NY., Liang. H., Yan. N* and K. Zhou* (2020). Upcycling chitin-containing waste into organonitrogen chemicals via an integrated process. Proceedings of the National Academy of Sciences 117(14).

5. Ma, X., H. Liang., X. Cui., Y. Liu., H. Lu., W. Ning and K. Zhou* (2019). A standard for near-scarless plasmid construction using reusable DNA parts.  Nature Communications 10, 3294.

6. Ma, X., H. Liang, K. Zhou. (2019). Constructing plasmid under GT DNA assembly standard. Protocol Exchange, doi.org/10.21203/rs.2.10082/v1.

7. Ma, X., H. Liang., C. Ning., S. Deng and E. Su* (2017).  Integrating a light-driven coenzyme regeneration system by expression of an alcohol dehydrogenase in phototrophic bacterium for synthesis of chiral alcohol. Journal of Biotechnology 259: 120-125.

8. Ma, X., Y. Zhu., M. Sun., S. Yang., E. Su* and D. Wei* (2016). High-level expression of Cephalosporin C deacetylase from Bacillus subtilis SIL 3 in Escherichia coli by a multilevel collaborative strategy. Biochemical Engineering Journal 114: 183-190.

9. Deng, S., X. Ma (Co-first author)., M. Sun., D. Wei* and E. Su* (2016). Efficient enzymatic synthesis of ampicillin using mutant Penicillin G acylase with bio-based solvent glycerol. Catalysis Communications 79: 31-34.

10. Deng, S., X. Ma (Co-first author)., E. Su* and D. Wei* (2016). Efficient cascade synthesis of ampicillin from penicillin G potassium salt using wild and mutant penicillin G acylase from Alcaligenes faecalis. Journal of biotechnology 219: 142-148.

11. Ma, X., E. Su., S. Deng* and D. Wei* (2015). An effective method for extraction of glutaryl-7-aminocephalosporanic acid acylase from recombinant E. coli cells. Biotechnology and Bioprocess Engineering 20(4): 718-724.

12. Zhu, S., X. Ma (Co-first author)., E. Su* and D. Wei* (2015). Efficient hydration of 2-amino-2, 3-dimethylbutyronitrile to 2-amino-2, 3-dimethylbutyramide in a biphasic system via an easily prepared whole-cell biocatalyst. Green Chemistry 17(7): 3992-3999.

13. Ma, X., S. Deng., E. Su* and D. Wei* (2015). One-pot enzymatic production of deacetyl-7-aminocephalosporanic acid from cephalosporin C via immobilized cephalosporin C acylase and deacetylase. Biochemical Engineering Journal 95: 1-8.

14. Ma, X., E. Su*., Y. Zhu., S. Deng and D. Wei* (2013). High-level expression of glutaryl-7-aminocephalosporanic acid acylase from Pseudomonas diminuta NK703 in Escherichia coli by combined optimization strategies. Journal of biotechnology 168(4): 607-615.

 

专利：

1. K. Zhou., Ma, X. and H. Liang and (2017). Ligation and/or Assembly of Nucleic Acid Molecules. (PCT WO/2019/083,449).

 

招聘和招生：    

        欢迎对食品合成生物学技术开发感兴趣的研究人员加入，目前博士后、专职科研人员及科研助理均有职位开放招聘。同时欢迎感兴趣申请硕士、博士研究生的同学咨询。联系邮箱：xq_ma@sjtu.edu.cn