王    恒 职       称：助理研究员 所属学科：食品科学与工程 研究方向：风味科学与健康养老 电       话：021-34205873 电子信箱：wangheng0802@sjtu.edu.cn

个人简历

金沙2004路线js5助理研究员，2018年博士毕业于韩国釜山大学；2018年10月在上海交大生命学院生物信息学与生物统计学系开展博士后研究；2023年10月加入上海交大农生学院“芳香材料与风味科学”团队。担任上海植物学会药用植物与植物药专委会委员，中国生物工程学会计算生物学与生物信息学专委会委员，Interdisciplinary Sciences-Computational Life Sciences杂志青年编委。主要研究方向：（1）香气分子调控神经系统性疾病机制；（2）人工智能在美丽大健康产业中的应用；（3）长效缓释香精分子设计与香气控释机制探究；（4）嗅觉受体识别气味图谱构建。近5年以第一/通讯作者发表论文十余篇，申请国际国家发明专利二十余项，已获授权十余项。

代表性论文

1. Bo-Yong Hu^#, Heng Wang^#, Hong Liang, Ning Ma, Diyi Wu, Ruotong Zhao, Haoming Lv, Zuobing Xiao*. Multiple effcts of spicy flavors on neurological diseases through the intervention of TRPV1: a critical review. Critical Reviews in Food Science and Nutrition, 1549-7852，2024.
2. Ali Arif, Masood Adan, Khan Abdul Aziz, Zhu FengYun, Cheema Muhammad Arslan Rasheed, Abdus Samad, Abdul Wadood, Abbas Khan, Qiu Yu, Wang Heng*, Wei DongQing*. Comparative binding analysis of WGX50 and Alpha-M with APP family proteins APLP1 and APLP2 using structural-dynamics and free energy calculation approaches. Physical chemistry chemical physics : PCCP. 2023.
3. Khan Abbas^#, Heng Wang^#, Imran Kashif,Zhu Guanghao,Ji Jun,Zhang Yani,Guan Xiaoqing,Ge Guangbo,Wei DongQing. Discovery of Isojacareubin as a covalent inhibitor of SARS-CoV-2 main protease using structural and experimental approaches.[J] Journal of medical virology, 2023,95(2).
4. Abbas Khan, Taimoor Khan, Shughla Ali, Summiya Aftab, Yanjing Wang, Wang Qiankun, Mazhar Khan, Muhammad Suleman, Shahid Ali, Wang Heng*,  Dong-Qing Wei*, Anwar Mohammad. SARS-CoV-2 new variants: characteristic features and impact on the efficacy of different vaccines. Biomedicine & Pharmacotherapy, 2021,Volume 143.
5. Abbas Khan;Wang Heng*;Yanjing Wang;Jingfei Qiu;Xiaoyong Wei;Shaoliang Peng;Shoaib Saleem;Mazhar Khan;Syed Shujait Ali;Dong‐Qing Wei;  In silico and in vitro evaluation of Kaempferol as a potential inhibitor of the SARS-CoV-2 main protease (3CLpro). Phytotherapy Research, 2021.
6. Khan, Abbas; Rehman, Zainab; Hashmi, Huma Farooque; Khan, Abdul Aziz; Junaid, Muhammad; Sayaf, Abrar Mohammad; Ali, Syed Shujait; Hassan, Fakhr Ul; Heng, Wang*; Wei, Dong-Qing*. An Integrated Systems Biology and Network-Based Approaches to Identify Novel Biomarkers in Breast Cancer Cell Lines Using Gene Expression Data. Interdisciplinary Sciences: Computational Life Sciences, 2020.
7. Wang, Heng; Ham, Tae-Ho; Im, Da-Eun; Lar, San Mar; Jang, Seong-Gyu; Lee, Joohyun; Mo, Youngjun; Jeung, Ji-Ung; Kim, Sun Tae; Kwon, Soon-Wook.  A New SNP in Rice Gene Encoding Pyruvate Phosphate Dikinase (PPDK) Associated with Floury Endosperm. Genes, 2020.  
8. Wang, Heng; Park, So-Yeon; Song, Su-Hyang; San, Mar-Lar; Kim, Yong-Chul; Ham, Tae-Ho; Kim, Dong-Yong; Kim, Tae-Sung; Lee, Joohyun; Kwon, Soon-Wook. Analysis of complete chloroplast genome sequence of Korean landrace Cymbidium goeringii. 3 Biotech, 2018. 
9. Wang, Heng; Mo, Young-Jun; Im, Da-Eun; Jang, Seong-Gyu; Ham, Tae-Ho; Lee, Joohyun; Jeung, Ji-Ung; Kwon, Soon-Wook. A new SNP in cyOsPPDK gene is associated with floury endosperm in Suweon 542. Molecular Genetics and Genomics, 2018.

授权专利

1. 魏冬青，王恒 花椒提取物中活性成分WGX50的新用途（专利号：ZL 2020 1 0551170.4）
2. 魏冬青，王恒，王艳菁，王乾坤 基于分子模拟发现山柰酚在COVID-19病毒中的新用途 （专利号：ZL 2020 1 0247402.7）
3. 魏冬青，李代禧，王恒，王艳菁 蛋白药物活性的分子保护及其处方设计方法 （专利号：ZL 2020 1 1415745.6 ）
4. 魏冬青，李代禧，王恒，王艳菁 小分子药物特定晶形的分子调控方法 （专利号：ZL 2020 1 1411510.X）
5. 魏冬青，法哈德，王恒，王艳菁  全血细胞计数在预测SARS-CoV-2感染中的应用（专利号：ZL2020 1 1314648.8）
6. 魏冬青，莫达·沙扎德·洛迪，阿里夫·马里克，穆罕默德·塔希尔·汗，塞拉·阿夫塔布，扎胡尔·卡迪尔·萨姆拉，王恒，王艳菁  纳米靶向药物的制备方法及其在治疗胃癌中的应用（专利号：ZL 2020 1 1525066.4）
7. 魏冬青，马迪哈·沙赫扎德·洛迪，阿伊莎·沙欣，穆罕默德·塔希尔·汗，伊姆蒂亚兹·沙菲克，扎胡尔·萨姆拉，王恒，王艳菁  一种半乳糖醛酸磁性纳米颗粒纯化聚半乳 糖醛酸酶的方法 （专利号：ZL 202110030728.9）
8. 赵卫国，王恒，李凤，钱姣，方荣俊，刘利  桑树非生物胁迫特异性表达的启动子及其应用  （专利号：ZL 2014 1 0472985.8）
9. Wei Dongqing, Wang Heng. Mechanism of skin aging reversal by active ingredient WGX-50 of Zanthoxylum bungeanum Maxim (Patent number: 2021104838)
10. Wang Heng, Wei Dongqing. Extraction method of active ingredient WGX-50 from Zanthoxylum bungeanum and its application in cosmetics (Patent number: 2021105282)
11. Wang Heng, Wei Dongqing. Multi-effect Cosmetic Composition Containing Suberosin and Preparation Method thereof (Patent number: 2021105695 )